SYSTANE® Products for Healthy Vision and Dry Eye Relief
There’s a SYSTANE® product that’s right for your patients, whether they need relief from dry eye symptoms or support for healthy vision.*
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Eye Drops for Dry Eyes
SYSTANE® COMPLETE Preservative-Free Eye Drops
Delivers optimal dry eye symptom relief, fast hydration, and tear evaporation protection with a preservative-free formula.1-3
SYSTANE® COMPLETE Lubricant Eye Drops
Made up of tiny, nano-sized droplets, this soothing eye drop forms a matrix of protection across the ocular surface.1-3
SYSTANE® HYDRATION Preservative-Free Eye Drops
Long-lasting hydration to help restore moisture to dry eyes with soothing, preservative-free relief of HydroBoost technology.4-6
SYSTANE® ULTRA Lubricant Eye Drops
Clinically proven to deliver extended protection for high-performance dry eye symptom relief that lasts.5,7
SYSTANE® ULTRA Preservative-Free Eye Drops
Get the same high-performance dry eye symptom relief of SYSTANE® ULTRA Lubricant Eye Drops in a preservative-free formula.5,7
SYSTANE® BALANCE Lubricant Eye Drops
Help support and restore the eyes’ delicate lipid layer by replenishing essential moisture.8
SYSTANE® Lubricant Eye Drops
Dry eye relief in the original formula that made SYSTANE® the #1 doctor recommended brand for dry eye symptom relief.9
SYSTANE® Preservative-Free Eye Drops
Relieve mild dry eye symptoms with a preservative-free formula perfect for sensitive eyes.
SYSTANE® CONTACTS Rewetting Eye Drops
Moisten lenses and help remove debris that may cause irritation and discomfort.
Preservative-Free Eye Drops for Dry Eye
SYSTANE® COMPLETE Preservative-Free Eye Drops
Delivers optimal dry eye symptom relief, fast hydration, and tear evaporation protection with a preservative-free formula.1-3
SYSTANE® HYDRATION Preservative-Free Eye Drops
Long-lasting hydration to help restore moisture to dry eyes with soothing, preservative-free relief of HydroBoost technology.4-6
SYSTANE® ULTRA Preservative-Free Eye Drops
Get the same high-performance dry eye symptom relief of SYSTANE® ULTRA Lubricant Eye Drops in a preservative-free formula.5,7
SYSTANE® Preservative-Free Eye Drops
Relieve mild dry eye symptoms with a preservative-free formula perfect for sensitive eyes.
Eye Drops for Allergy Relief
SYSTANE® ZADITOR® Antihistamine Eye Drops
The original triple-action, prescription-strength formula that works in minutes to deliver up to 12 hours of eye itch relief.10
Gels & Ointments for Dry Eye
SYSTANE® Nighttime Eye Ointment
Designed to keep eyes lubricated and comfortable at night.
SYSTANE® Lubricant Eye Gel
The thickest gel formulation to coat the eye with a strong layer of dry eye symptom protection.
SYSTANE® Gel Drops
Provides lasting relief from dry eye irritation.11 A thicker eye drop formulation that creates a protective shield over eyes.
SYSTANE® Day & Night Eye Drops
Packs include SYSTANE® ULTRA for comfort during the day, and SYSTANE® Gel Drops for extra protection at night.
Eye Vitamins & Lid Wipes
SYSTANE® ICAPS® Eye Vitamin AREDS 2 Formula Softgels
Supports eye health in people with Age-Related Macular Degeneration (AMD).*
SYSTANE® ICAPS® Eye Vitamin AREDS Formula Coated Tablets
Contains ingredients used in the Age-Related Eye Disease Study (AREDS) conducted by the National Eye Institute.
SYSTANE® ICAPS® Eye Vitamin Multivitamin Formula Coated Tablets
Combines eye and body vitamin and mineral needs in one formulation for added convenience.
SYSTANE® ICAPS® Eye Vitamin Vision Health Formula Softgels
A wide spectrum of important ingredients shown to support eye health in people at risk for age-related macular changes.*
SYSTANE® ICAPS® Eye Vitamin Lutein & Zeaxanthin Formula
Specialized, comprehensive formula of carotenoids, antioxidants and minerals that are important to vision.*
SYSTANE® Lid Wipes
Premium, pre-moistened eyelid cleansing wipes that can be used as part of a daily hygiene regimen.
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
In-Office Treatment
SYSTANE® iLux®
Treatment directly to the blocked meibomian glands with the goal of clearing any obstructions.
SYSTANE® iLux2®
Treatment directly to the blocked meibomian glands with the goal of clearing any obstructions.
Indication: The Systane® iLux® and Systane® iLux2® are indicated for the application of localized heat and pressure therapy in adult patients with meibomian gland dysfunction (MGD), which is associated with evaporative dry eye. Systane® iLux2® also captures/stores digital images and video of the meibomian glands.
Potential Adverse Reactions: Potential adverse effects may occur because of the procedure. These effects include but are not limited to, the onset or increase in: eyelid/eye pain requiring discontinuation of the treatment procedure, eyelid irritation or inflammation, temporary reddening of the skin, ocular surface irritation or inflammation (e.g., corneal abrasion, conjunctival edema or conjunctival injection (hyperemia)), and ocular symptoms (e.g., burning, stinging, tearing, itching, discharge, redness, foreign body sensation, visual disturbance, sensitivity to light).
Attention: Please refer to the User Manuals for a complete list of contraindications, instructions for use, warnings and precautions for Systane® iLux® and Systane® iLux2®.
ALL SYSTANE® Products
SYSTANE® COMPLETE Preservative-Free Eye Drops
Delivers optimal dry eye symptom relief, fast hydration, and tear evaporation protection with a preservative-free formula.1-3
SYSTANE® COMPLETE Lubricant Eye Drops
Made up of tiny, nano-sized droplets, this soothing eye drop forms a matrix of protection across the ocular surface.1-3
SYSTANE® HYDRATION Preservative-Free Eye Drops
Long-lasting hydration to help restore moisture to dry eyes with soothing, preservative-free relief of HydroBoost technology.4-6
SYSTANE® ULTRA Lubricant Eye Drops
Clinically proven to deliver extended protection for high-performance dry eye symptom relief that lasts.5,7
SYSTANE® ULTRA Preservative-Free Eye Drops
Get the same high-performance dry eye symptom relief of SYSTANE® ULTRA Lubricant Eye Drops in a preservative-free formula.5,7
SYSTANE® BALANCE Lubricant Eye Drops
Help support and restore the eyes’ delicate lipid layer by replenishing essential moisture.8
SYSTANE® Lubricant Eye Drops
Dry eye relief in the original formula that made SYSTANE® the #1 doctor recommended brand for dry eye symptom relief.9
SYSTANE® Preservative-Free Eye Drops
Relieve mild dry eye symptoms with a preservative-free formula perfect for sensitive eyes.
SYSTANE® CONTACTS Rewetting Eye Drops
Moisten lenses and help remove debris that may cause irritation and discomfort.
SYSTANE® ZADITOR® Antihistamine Eye Drops
The original triple-action, prescription-strength formula that works in minutes to deliver up to 12 hours of eye itch relief.10
SYSTANE® Lubricant Eye Drops
Designed to keep eyes lubricated and comfortable at night.
SYSTANE® Lubricant Eye Gel
The thickest gel formulation to coat the eye with a strong layer of dry eye symptom protection.
SYSTANE® Gel Drops
Provides lasting relief from dry eye irritation.11 A thicker eye drop formulation that creates a protective shield over eyes.
SYSTANE® Day & Night Eye Drops
Packs include SYSTANE® ULTRA for comfort during the day, and SYSTANE® Gel Drops for extra protection at night.
SYSTANE® ICAPS® Eye Vitamin AREDS 2 Formula Softgels
Supports eye health in people with Age-Related Macular Degeneration (AMD).*
SYSTANE® ICAPS® Eye Vitamin AREDS Formula Coated Tablets
Contains ingredients used in the Age-Related Eye Disease Study (AREDS) conducted by the National Eye Institute.
SYSTANE® ICAPS® Eye Vitamin Multivitamin Formula Coated Tablets
Combines eye and body vitamin and mineral needs in one formulation for added convenience.
SYSTANE® ICAPS® Eye Vitamin Vision Health Formula Softgels
A wide spectrum of important ingredients shown to support eye health in people at risk for age-related macular changes.*
SYSTANE® ICAPS® Eye Vitamin Lutein & Zeaxanthin Formula
Specialized, comprehensive formula of carotenoids, antioxidants and minerals that are important to vision.*
SYSTANE® Lid Wipes
Premium, pre-moistened eyelid cleansing wipes that can be used as part of a daily hygiene regimen.
SYSTANE® iLux®
Treatment directly to the blocked meibomian glands with the goal of clearing any obstructions.
SYSTANE® iLux2®
Treatment directly to the blocked meibomian glands with the goal of clearing any obstructions.
Indication: The Systane® iLux® and Systane® iLux2® are indicated for the application of localized heat and pressure therapy in adult patients with meibomian gland dysfunction (MGD), which is associated with evaporative dry eye. Systane® iLux2® also captures/stores digital images and video of the meibomian glands.
Potential Adverse Reactions: Potential adverse effects may occur because of the procedure. These effects include but are not limited to, the onset or increase in: eyelid/eye pain requiring discontinuation of the treatment procedure, eyelid irritation or inflammation, temporary reddening of the skin, ocular surface irritation or inflammation (e.g., corneal abrasion, conjunctival edema or conjunctival injection (hyperemia)), and ocular symptoms (e.g., burning, stinging, tearing, itching, discharge, redness, foreign body sensation, visual disturbance, sensitivity to light).
Attention: Please refer to the User Manuals for a complete list of contraindications, instructions for use, warnings and precautions for Systane® iLux® and Systane® iLux2®.
1. Silverstein S, Yeu E, Tauber J, et al. Symptom Relief Following a Single Dose of Propylene Glycol-Hydroxypropyl Guar Nanoemulsion in Patients with Dry Eye Disease: A Phase IV, Multicenter Trial. Clin Ophthalmol. 2020;14:3167-3177.
2. Rangarajan R, Ketelson H. Preclinical evaluation of a new hydroxypropyl-guar phospholipid nanoemulsion-based artificial tear formulation in models of corneal epithelium. J Ocul Pharmacol Ther. 2019;35(1):32-37.
3. Ketelson H, Rangarajan R. Pre-clinical evaluation of a novel phospholipid nanoemulsion based lubricant eye drops. Poster presented at ARVO 2017, Baltimore, MD.
4. Rangarajan R, Kraybill B, Ogundele A, Ketelson H. Effects of a Hyaluronic Acid/Hydroxypropyl Guar Artificial Tear Solution on Protection, Recovery, and Lubricity in Models of Corneal Epithelium. J. Ocul Pharmacol Ther. 2015;31(8):491-497.
5. Davitt WF, Bloomenstein M, Christensen M, Martin AE. Efficacy in patients with dry eye after treatment with a new lubricant eye drop formulation. J Ocul Pharmacol Ther. 2010;26(4):347-353.
6. Rolando M, Autori S, Badino F, Barabino S. Protecting the ocular surface and improving the quality of life of dry eye patients: a study of the efficacy of an HP-guar containing ocular lubricant in a population of dry eye patients. J Ocul Pharmacol Ther. 2009;25(3):271-278.
7. Christensen MT, Martin AE, Bloomenstein M. A comparison of efficacy between Systane Ultra and Optive lubricant eye drops when tested with dry eye patients. Optometry. 2009;80(6):315.
8. Benelli U. Systane lubricant eye drops in the management of ocular dryness. Clin Ophthalmol. 2011:5;783-790.
9. Based on IQVIA ProVoice Survey of Eye Care Professionals 12 months ending December 31, 2021.
10. Greiner JV, Minno G. A placebo-controlled comparison of ketotifen fumarate and nedocromil sodium ophthalmic solutions for the prevention of ocular itching with the conjunctival allergen challenge model. Clin Ther. 2003;25(7):1988-2005.
11. Christensen M, Martin A, Meadows D. An evaluation of the efficacy and patient acceptance of a new lubricant eye gel. The American Academy of Optometry Annual Meeting; 2011; E-Abstract 115013.