1 drop.
8 hours
dry eye relief.2
Our most advanced dry eye solution, preservative-free
![New Systane Complete Preservative-free Lubricating Eye Drops box and multi-dose bottle](/sites/g/files/rbvwei2521/files/2022-07/systane-eyedrops-2-1.png)
SYSTANE® COMPLETE Preservative-Free
See how the technology and science of SYSTANE® COMPLETE PF supports all layers of the tear film and protects against tear evaporation3,4
![white eye drop icon](/sites/g/files/rbvwei2521/files/2022-04/icon-container---_-CHANGE-PADDING-WITHIN-CIRCLE-HERE_7.png)
![white eye drop icon](/sites/g/files/rbvwei2521/files/2022-04/icon-container---_-CHANGE-PADDING-WITHIN-CIRCLE-HERE_7.png)
An aging population, pollution, and an increase in the use of digital devices all contribute to the rapidly growing dry eye market5,6
![doughnut chart showing 86%](/sites/g/files/rbvwei2521/files/2022-04/Group%20196.png)
![doughnut chart showing 86%](/sites/g/files/rbvwei2521/files/2022-04/Group%20196.png)
86% of dry eye sufferers have clinical signs of Meibomian Gland Dysfunction and may benefit from a drop like SYSTANE® COMPLETE PF7
SYSTANE® COMPLETE Preservative-Free gives your patients what they want
Effective | Provides immediate and lasting symptom relief
![Three charts showing percentage ranges of no-to-mild discomfort after using one drop of Systane Complete Preservative-Free eye drops (at 0, 4, and 8 hr mark)](/sites/g/files/rbvwei2521/files/2022-04/content-colums%20--_%20ADJUST-MARGIN%20TO%20CHANGE%20HEIGHT%20OF%20COMPONENT_0.png)
![Three charts showing percentage ranges of no-to-mild discomfort after using one drop of Systane Complete Preservative-Free eye drops (at 0, 4, and 8 hr mark)](/sites/g/files/rbvwei2521/files/2022-04/content-colums%20--_%20ADJUST-MARGIN%20TO%20CHANGE%20HEIGHT%20OF%20COMPONENT_0.png)
*Based on 45.5% of baseline patients, who reported moderate to severe symptoms; n=61
Ergonomic | New multi-dose bottle is designed for easier handling and less drop spillage.*
86%
of patients prefer MDPF packaging
over unit-dose vials8**
94%
of ECPs said the bottle
used for SYSTANE® MDPF products
is easy and intuitive8†
*vs. usage of unit-dose vials
**n=155
†n=17
![hand holding ergonomic multi-dose bottle of Systane Complete Preservative-Free](/sites/g/files/rbvwei2521/files/2022-04/col-left.png)
Economical
Helps with a recommendation barrier of preservative-free artificial tears based on cost.9
*Compared to SYSTANE® HYDRATION PF UD vials.
![Woman having conversation with her doctor, both wearing masks](/sites/g/files/rbvwei2521/files/2022-04/col-right_3.png)
Environment | Multi-dose bottle reduces packaging and plastic waste
Saves nearly two pounds of plastic per customer per year10*
- One multi-dose bottle replaces 120 unit-dose vials10**
- ~96% reduction in plastic vs. unit-dose preservative-free vials10*
*Based on two drops per eye of SYSTANE® COMPLETE Preservative-Free per day and two unit-dose vials of dry eye drops per day.
**Calculation based on comparison of SYSTANE® COMPLETE PF vs. SYSTANE® HYDRATION UD; 1 drop per eye per dose.
![Systane Complete Preservative-Free multi-dose bottle sitting on top of many plastic unit-dose vials](/sites/g/files/rbvwei2521/files/2022-04/col-right_2.png)
Explore the rest of the SYSTANE® portfolio
1. Based on IQVIA ProVoice Survey of Eye Care Professionals 12 months ending December 31, 2021.
2. Silverstein S, Yeu E, Tauber J, et al. Symptom Relief Following a Single Dose of Propylene Glycol-Hydroxypropyl Guar Nanoemulsion in Patients with Dry Eye Disease: A Phase IV, Multicenter Trial. Clin Ophthalmol. 2020;14:3167-3177.
3. Rangarajan R, Ketelson H. Preclinical evaluation of a new hydroxypropyl-guar phospholipid nanoemulsion-based artificial tear formulation in models of corneal epithelium. J Ocul Pharmacol Ther. 2019;35(1):32-37.
4. Ketelson H, Rangarajan R. Pre-clinical evaluation of a novel phospholipid nanoemulsion based lubricant eye drops. Poster presented at ARVO 2017, Baltimore, MD.
5. MarketScope LLC. 2020 Dry Eye Products Report: A Global Market Analysis for 2019 to 2025. St. Louis, MO: MarketScope LLC; 2020.
6. Farrand KF, Fridman M, Stillman IÖ, Schaumberg DA. Prevalence of Diagnosed Dry Eye Disease in the United States Among Adults Aged 18 Years and Older. Am J Ophthalmol. 2017;182:90-98.
7. Lemp MA, Crews LA, Bron AJ, Foulks GN, Sullivan BD. Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study. Cornea. 2012;31:472-478.
8. Based on a survey of 155 patients and 17 eye care professionals in Canada; patients used SYSTANE® HYDRATION MDPF for one month before taking survey; Alcon data on file, 2021.
9. Alcon data on file, 2021.
10. Alcon data on file, 2021.
©2022 Alcon Inc. US-SYX-2200002